161Tb Purification by High Performance Ion Chromatography (HPIC) from Irradiated 160Gd

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Abstract

161Tb has many attractive properties (halflife of 6.9 d, β- decay energy of 593 keV, conversion and Auger electron emission) for targeted radionuclide therapy with peptides and antibodies [1]. 161Tb can be produced via neutron irradiation of 160Gd in a nuclear reactor, such as BR2 (flux of circa 1014 neutrons cm-2 s-1) at SCK•CEN. The aim of this project was to develop a fast and easy method to purify small amounts (circa 250 MBq) of n.c.a. 161Tb with high specific activity, for radiolabeling studies and in-house chelator design.

Details

Original languageEnglish
Title of host publicationAnnual Congress of the European Association of Nuclear Medicine October 12 – 16, 2019 Barcelona, Spain
PagesS40
Number of pages1
Volume46
DOIs
Publication statusPublished - 31 Dec 2019
Event2019 - EANM: European Association of Nuclear Medicine - Barcelona, Barcelona, Spain
Duration: 12 Oct 201916 Oct 2019
https://eanm19.eanm.org/
https://eanm19.eanm.org
https://www.efomp.org/index.php?r=events/view&id=83

Publication series

NameEuropean Journal of Nuclear Medicine and Molecular Imaging
PublisherSpringer
ISSN (Print)1619-7070

Conference

Conference2019 - EANM
Abbreviated titleEANM
Country/TerritorySpain
CityBarcelona
Period2019-10-122019-10-16
Internet address

Keywords

  • Chromatography, 161Tb, Radionuclide therapy

ID: 7323697