161Tb Purification by High Performance Ion Chromatography (HPIC) from Irradiated 160Gd
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Abstract
161Tb has many attractive properties (halflife of 6.9 d, β- decay energy of 593 keV, conversion and Auger electron emission) for targeted radionuclide therapy with peptides and antibodies [1]. 161Tb can be produced via neutron
irradiation of 160Gd in a nuclear reactor, such as BR2 (flux of circa 1014 neutrons cm-2 s-1) at SCK•CEN. The aim of this project was to develop a fast and easy method to purify small amounts (circa 250 MBq) of n.c.a. 161Tb with high specific activity, for radiolabeling studies and in-house chelator design.
Details
| Original language | English |
|---|---|
| Title of host publication | Annual Congress of the European Association of Nuclear Medicine October 12 – 16, 2019 Barcelona, Spain |
| Pages | S40 |
| Number of pages | 1 |
| Volume | 46 |
| DOIs | |
| Publication status | Published - 31 Dec 2019 |
| Event | 2019 - EANM: European Association of Nuclear Medicine - Barcelona, Barcelona, Spain Duration: 12 Oct 2019 → 16 Oct 2019 https://eanm19.eanm.org/ https://eanm19.eanm.org https://www.efomp.org/index.php?r=events/view&id=83 |
Publication series
| Name | European Journal of Nuclear Medicine and Molecular Imaging |
|---|---|
| Publisher | Springer |
| ISSN (Print) | 1619-7070 |
Conference
| Conference | 2019 - EANM |
|---|---|
| Abbreviated title | EANM |
| Country/Territory | Spain |
| City | Barcelona |
| Period | 2019-10-12 → 2019-10-16 |
| Internet address |
Keywords
- Chromatography, 161Tb, Radionuclide therapy
ID: 7323697