A comparative neutron activation analysis study of common generic manipulated and reference medicines commercialized in Brazil

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Abstract

In this work, a comparative study of neutron activation analysis (NAA) was performed by the nuclear institutes: CDTN/CNENBrazil, CCHEN-Chile and the SCK.CEN-Belgium aiming to investigate some generic, manipulated and reference medicines largelycommercialized in Brazil. Some impurities such as: As, Ba, Br, Ce, Co, Cr, Eu, Fe, Hf, Sb, Sc, Sm, Ti and Zn were found, and the heterogeneity of the samples pointed out the lack of an efficient public system of quality control.

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Original languageEnglish
Pages (from-to)1307-1312
JournalApplied Radiation and Isotopes
Volume66
Issue number10
DOIs
Publication statusPublished - 7 Mar 2008

Keywords

  • Neutron activation analysis, Generic medicines, Manipulated medicines

ID: 175290