A comparative neutron activation analysis study of common generic manipulated and reference medicines commercialized in Brazil

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A comparative neutron activation analysis study of common generic manipulated and reference medicines commercialized in Brazil. / Leal, A.S.; Menezes, M.A.B.C.; Rodrigues, R.R.; Andonie, O.; Vermaercke, Peter; Sneyers, Liesel.

In: Applied Radiation and Isotopes, Vol. 66, No. 10, 07.03.2008, p. 1307-1312.

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Leal, A.S. ; Menezes, M.A.B.C. ; Rodrigues, R.R. ; Andonie, O. ; Vermaercke, Peter ; Sneyers, Liesel. / A comparative neutron activation analysis study of common generic manipulated and reference medicines commercialized in Brazil. In: Applied Radiation and Isotopes. 2008 ; Vol. 66, No. 10. pp. 1307-1312.

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@article{f35afedd2e6241c79dba26a425166467,
title = "A comparative neutron activation analysis study of common generic manipulated and reference medicines commercialized in Brazil",
abstract = "In this work, a comparative study of neutron activation analysis (NAA) was performed by the nuclear institutes: CDTN/CNENBrazil, CCHEN-Chile and the SCK.CEN-Belgium aiming to investigate some generic, manipulated and reference medicines largelycommercialized in Brazil. Some impurities such as: As, Ba, Br, Ce, Co, Cr, Eu, Fe, Hf, Sb, Sc, Sm, Ti and Zn were found, and the heterogeneity of the samples pointed out the lack of an efficient public system of quality control.",
keywords = "Neutron activation analysis, Generic medicines, Manipulated medicines",
author = "A.S. Leal and M.A.B.C. Menezes and R.R. Rodrigues and O. Andonie and Peter Vermaercke and Liesel Sneyers",
note = "Score = 10",
year = "2008",
month = "3",
day = "7",
doi = "10.1016/j.apradiso.2008.03.004",
language = "English",
volume = "66",
pages = "1307--1312",
journal = "Applied Radiation and Isotopes",
issn = "0969-8043",
publisher = "Elsevier",
number = "10",

}

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TY - JOUR

T1 - A comparative neutron activation analysis study of common generic manipulated and reference medicines commercialized in Brazil

AU - Leal, A.S.

AU - Menezes, M.A.B.C.

AU - Rodrigues, R.R.

AU - Andonie, O.

AU - Vermaercke, Peter

AU - Sneyers, Liesel

N1 - Score = 10

PY - 2008/3/7

Y1 - 2008/3/7

N2 - In this work, a comparative study of neutron activation analysis (NAA) was performed by the nuclear institutes: CDTN/CNENBrazil, CCHEN-Chile and the SCK.CEN-Belgium aiming to investigate some generic, manipulated and reference medicines largelycommercialized in Brazil. Some impurities such as: As, Ba, Br, Ce, Co, Cr, Eu, Fe, Hf, Sb, Sc, Sm, Ti and Zn were found, and the heterogeneity of the samples pointed out the lack of an efficient public system of quality control.

AB - In this work, a comparative study of neutron activation analysis (NAA) was performed by the nuclear institutes: CDTN/CNENBrazil, CCHEN-Chile and the SCK.CEN-Belgium aiming to investigate some generic, manipulated and reference medicines largelycommercialized in Brazil. Some impurities such as: As, Ba, Br, Ce, Co, Cr, Eu, Fe, Hf, Sb, Sc, Sm, Ti and Zn were found, and the heterogeneity of the samples pointed out the lack of an efficient public system of quality control.

KW - Neutron activation analysis

KW - Generic medicines

KW - Manipulated medicines

UR - http://ecm.sckcen.be/OTCS/llisapi.dll/open/ezp_90177

UR - http://knowledgecentre.sckcen.be/so2/bibref/5059

U2 - 10.1016/j.apradiso.2008.03.004

DO - 10.1016/j.apradiso.2008.03.004

M3 - Article

VL - 66

SP - 1307

EP - 1312

JO - Applied Radiation and Isotopes

JF - Applied Radiation and Isotopes

SN - 0969-8043

IS - 10

ER -

ID: 175290