Assessing Organ Doses from Paediatric CT Scans—A Novel Approach for an Epidemiology Study

Research output: Contribution to journalArticle

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Assessing Organ Doses from Paediatric CT Scans—A Novel Approach for an Epidemiology Study. / Thierry-Chef, Isabelle; Dabin, Jérémie; Friberg, Eva; Hermen, Johannes; Istad, Tore; Jahnen, Andreas; Krille, Lucian; Lee, Choonsik; Maccia, Carlo; Nordenskjöld, Arvid; Olerud, Hilde; Rani, Kaddour; Rehel, Jean-Luc; Simon, Steven; Struelens, Lara; Kesminiene, Ausrele.

In: International Journal of Environmental Research and Public Health, Vol. 10, No. 2, 18.02.2013, p. 717-728.

Research output: Contribution to journalArticle

Harvard

Thierry-Chef, I, Dabin, J, Friberg, E, Hermen, J, Istad, T, Jahnen, A, Krille, L, Lee, C, Maccia, C, Nordenskjöld, A, Olerud, H, Rani, K, Rehel, J-L, Simon, S, Struelens, L & Kesminiene, A 2013, 'Assessing Organ Doses from Paediatric CT Scans—A Novel Approach for an Epidemiology Study', International Journal of Environmental Research and Public Health, vol. 10, no. 2, pp. 717-728. https://doi.org/10.3390/ijerph10020717

APA

Thierry-Chef, I., Dabin, J., Friberg, E., Hermen, J., Istad, T., Jahnen, A., ... Kesminiene, A. (2013). Assessing Organ Doses from Paediatric CT Scans—A Novel Approach for an Epidemiology Study. International Journal of Environmental Research and Public Health, 10(2), 717-728. https://doi.org/10.3390/ijerph10020717

Vancouver

Thierry-Chef I, Dabin J, Friberg E, Hermen J, Istad T, Jahnen A et al. Assessing Organ Doses from Paediatric CT Scans—A Novel Approach for an Epidemiology Study. International Journal of Environmental Research and Public Health. 2013 Feb 18;10(2):717-728. https://doi.org/10.3390/ijerph10020717

Author

Thierry-Chef, Isabelle ; Dabin, Jérémie ; Friberg, Eva ; Hermen, Johannes ; Istad, Tore ; Jahnen, Andreas ; Krille, Lucian ; Lee, Choonsik ; Maccia, Carlo ; Nordenskjöld, Arvid ; Olerud, Hilde ; Rani, Kaddour ; Rehel, Jean-Luc ; Simon, Steven ; Struelens, Lara ; Kesminiene, Ausrele. / Assessing Organ Doses from Paediatric CT Scans—A Novel Approach for an Epidemiology Study. In: International Journal of Environmental Research and Public Health. 2013 ; Vol. 10, No. 2. pp. 717-728.

Bibtex - Download

@article{c90f88301c8d4e2a988974ce607831df,
title = "Assessing Organ Doses from Paediatric CT Scans—A Novel Approach for an Epidemiology Study",
abstract = "The increasing worldwide use of paediatric computed tomography (CT) has led to increasing concerns regarding the subsequent effects of exposure to radiation. In response to this concern, the international EPI-CT project was developed to study the risk of cancer in a large multi-country cohort. In radiation epidemiology, accurate estimates of organ-specific doses are essential. In EPI-CT, data collection is split into two time periods—before and after introduction of the Picture Archiving Communication System (PACS) introduced in the 1990s. Prior to PACS, only sparse information about scanner settings is available from radiology departments. Hence, a multi-level approach was developed to retrieve information from a questionnaire, surveys, scientific publications, and expert interviews. For the years after PACS was introduced, scanner settings will be extracted from Digital Imaging and Communications in Medicine (DICOM) headers, a protocol for storing medical imaging data. Radiation fields and X-ray interactions within the body will be simulated using phantoms of various ages and Monte-Carlo-based radiation transport calculations. Individual organ doses will be estimated for each child using an accepted calculation strategy, scanner settings, and the radiation transport calculations. Comprehensive analyses of missing and uncertain dosimetry data will be conducted to provide uncertainty distributions of doses.",
keywords = "paediatric computed tomography, organ dose reconstruction, scanner settings, leukaemia, cancer risk",
author = "Isabelle Thierry-Chef and J{\'e}r{\'e}mie Dabin and Eva Friberg and Johannes Hermen and Tore Istad and Andreas Jahnen and Lucian Krille and Choonsik Lee and Carlo Maccia and Arvid Nordenskj{\"o}ld and Hilde Olerud and Kaddour Rani and Jean-Luc Rehel and Steven Simon and Lara Struelens and Ausrele Kesminiene",
note = "Score = 10",
year = "2013",
month = "2",
day = "18",
doi = "10.3390/ijerph10020717",
language = "English",
volume = "10",
pages = "717--728",
journal = "International Journal of Environmental Research and Public Health",
issn = "1660-4601",
publisher = "MDPI",
number = "2",

}

RIS - Download

TY - JOUR

T1 - Assessing Organ Doses from Paediatric CT Scans—A Novel Approach for an Epidemiology Study

AU - Thierry-Chef, Isabelle

AU - Dabin, Jérémie

AU - Friberg, Eva

AU - Hermen, Johannes

AU - Istad, Tore

AU - Jahnen, Andreas

AU - Krille, Lucian

AU - Lee, Choonsik

AU - Maccia, Carlo

AU - Nordenskjöld, Arvid

AU - Olerud, Hilde

AU - Rani, Kaddour

AU - Rehel, Jean-Luc

AU - Simon, Steven

AU - Struelens, Lara

AU - Kesminiene, Ausrele

N1 - Score = 10

PY - 2013/2/18

Y1 - 2013/2/18

N2 - The increasing worldwide use of paediatric computed tomography (CT) has led to increasing concerns regarding the subsequent effects of exposure to radiation. In response to this concern, the international EPI-CT project was developed to study the risk of cancer in a large multi-country cohort. In radiation epidemiology, accurate estimates of organ-specific doses are essential. In EPI-CT, data collection is split into two time periods—before and after introduction of the Picture Archiving Communication System (PACS) introduced in the 1990s. Prior to PACS, only sparse information about scanner settings is available from radiology departments. Hence, a multi-level approach was developed to retrieve information from a questionnaire, surveys, scientific publications, and expert interviews. For the years after PACS was introduced, scanner settings will be extracted from Digital Imaging and Communications in Medicine (DICOM) headers, a protocol for storing medical imaging data. Radiation fields and X-ray interactions within the body will be simulated using phantoms of various ages and Monte-Carlo-based radiation transport calculations. Individual organ doses will be estimated for each child using an accepted calculation strategy, scanner settings, and the radiation transport calculations. Comprehensive analyses of missing and uncertain dosimetry data will be conducted to provide uncertainty distributions of doses.

AB - The increasing worldwide use of paediatric computed tomography (CT) has led to increasing concerns regarding the subsequent effects of exposure to radiation. In response to this concern, the international EPI-CT project was developed to study the risk of cancer in a large multi-country cohort. In radiation epidemiology, accurate estimates of organ-specific doses are essential. In EPI-CT, data collection is split into two time periods—before and after introduction of the Picture Archiving Communication System (PACS) introduced in the 1990s. Prior to PACS, only sparse information about scanner settings is available from radiology departments. Hence, a multi-level approach was developed to retrieve information from a questionnaire, surveys, scientific publications, and expert interviews. For the years after PACS was introduced, scanner settings will be extracted from Digital Imaging and Communications in Medicine (DICOM) headers, a protocol for storing medical imaging data. Radiation fields and X-ray interactions within the body will be simulated using phantoms of various ages and Monte-Carlo-based radiation transport calculations. Individual organ doses will be estimated for each child using an accepted calculation strategy, scanner settings, and the radiation transport calculations. Comprehensive analyses of missing and uncertain dosimetry data will be conducted to provide uncertainty distributions of doses.

KW - paediatric computed tomography

KW - organ dose reconstruction

KW - scanner settings

KW - leukaemia

KW - cancer risk

UR - http://ecm.sckcen.be/OTCS/llisapi.dll/open/ezp_127317

UR - http://knowledgecentre.sckcen.be/so2/bibref/10000

U2 - 10.3390/ijerph10020717

DO - 10.3390/ijerph10020717

M3 - Article

VL - 10

SP - 717

EP - 728

JO - International Journal of Environmental Research and Public Health

JF - International Journal of Environmental Research and Public Health

SN - 1660-4601

IS - 2

ER -

ID: 205410