Biological Responses after Low Doses X-ray Exposure: Gene Expression and Mechanistic Studies

Research output: ThesisDoctoral thesis

Institutes & Expert groups

Abstract

The health effects arising from exposure to low doses of ionizing radiation are increasing due to the extensive use of medical and diagnostic applications. One of the central questions in the field of radiation biology is understanding the health consequences of these low doses, where several factors like genetics, life-style, and lack of robust epidemiological studies are impeding well-validated conclusions. Within the context of this PhD, we aim to understand the biological responses after low dose exposures in both in vitro and in vivo studies.

Details

Original languageEnglish
Awarding Institution
  • UGent - Universiteit Gent
Supervisors/Advisors
  • Baatout, Sarah, Supervisor
  • Thierens, Hubert, Supervisor, External person
Place of PublicationGhent, Belgium
Publisher
  • UGent - Universiteit Gent
Print ISBNs9789038222981
Publication statusPublished - 28 Jan 2014

Keywords

  • low dose, health effects, in vitro, in vivo, whole blood, gene expression, GSEA, IMRT, monocytes, immune response

ID: 326912