Development of an in-house 188W/188Re generator

Research output: Contribution to report/book/conference proceedingsIn-proceedings paper

Institutes & Expert groups

  • KUL - Katholieke Universiteit Leuven

Documents & links

Abstract

188Re decays by emitting high-energy beta particles (Emax: 2.1 MeV, Eav: 784 keV), which can be used to kill targeted tumor cells. The short half-life (t1/2 = 16.9 h) of 188Re allows it to be used in targeted radionuclide therapy when linked to peptides or antibodies. 188Re decays with a 155 keV (15%) gamma emission suitable for imaging and dosimetry. Combining these properties make 188Re an ideal theranostic agent in clinical nuclear medicine. Furthermore, 188Re is readily available from a 188W/188Re generator which enables the use of nca 188Re in hospitals and remote locations [1].

Details

Original languageEnglish
Title of host publicationEuropean Journal of Nuclear Medicine and Molecular Imaging
Pages477
Number of pages478
Volume47
Editionsuppl. 1
DOIs
Publication statusPublished - 30 Oct 2020

Publication series

NameEuropean Journal of Nuclear Medicine and Molecular Imaging
PublisherSpringer
NumberSupplement 1
Volume47
ISSN (Print)1619-7070

Keywords

  • 188W/188Re generator, radiolabeling, chelator, in house

ID: 7071702