Diagnostic reference levels, deterministic and stochastic risks in pediatric interventional cardiology procedures

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Diagnostic reference levels, deterministic and stochastic risks in pediatric interventional cardiology procedures. / Rizk, Chadia; Fares, Georges; Vanhavere, Filip; Saliba, Zakhia; Farah, Jad.

In: Health physics, Vol. 118, No. 1, 01.01.2020, p. 85-95.

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Rizk, Chadia ; Fares, Georges ; Vanhavere, Filip ; Saliba, Zakhia ; Farah, Jad. / Diagnostic reference levels, deterministic and stochastic risks in pediatric interventional cardiology procedures. In: Health physics. 2020 ; Vol. 118, No. 1. pp. 85-95.

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@article{32e482f321dd4190929a339679f8af91,
title = "Diagnostic reference levels, deterministic and stochastic risks in pediatric interventional cardiology procedures",
abstract = "To establish diagnostic reference levels (DRLs) and investigate deterministic and stochastic risks in pediatric interventional cardiology (IC) procedures. Exposure parameters were retrospectively reviewed for 373 patients treated between May 2016 and November 2018 at a single specialized hospital. Weight specific DRLs were derived for pediatric IC procedures. Additionally, peak skin dose (Dskin,max) was measured using thermoluminescent dosimeters for a sample of 7 diagnostic and 43 therapeutic procedures. Finally, using PCXMC software, organ doses were computed and the risk of exposure-induced cancer death (REID) was estimated using the risk models of the Biological Effects of Ionizing Radiation VII committee. DRLs for ventricular septal defect (VSD) occlusions, lacking in the literature, in terms of air kerma at patient entrance reference point (388 and 629 mGy) and total air kerma-area product (28 and 61 Gycm2) were proposed for patients weight-groups 5 − <15 kg and 15 − <30 kg, respectively. The mean (range) Dskin,max was 15 (1–30)mGy and 94 (1–491) mGy for diagnostic and therapeutic procedures, respectively. Meanwhile, VSDocclusion involved the highest organ doses where the lungs, liver, stomach, and breasts mean doses were 57, 37, 6, and 10 mGy, respectively, and the associated REID were 0.5{\%} and 0.3{\%} in female and male patients, respectively. DRLs were proposed for pediatric IC procedures; these will help optimize patient exposure. Dskin,max values were lower than the 2 Gy threshold for skin injuries. Pediatric organ doses and the REID were the highest during VSD occlusion and may be critical for repetitive procedures.",
keywords = "operational topics, children, exposure, radiation, health effects",
author = "Chadia Rizk and Georges Fares and Filip Vanhavere and Zakhia Saliba and Jad Farah",
note = "Score=10",
year = "2020",
month = "1",
day = "1",
doi = "10.1097/HP.0000000000001114",
language = "English",
volume = "118",
pages = "85--95",
journal = "Health physics",
issn = "0017-9078",
publisher = "Wolters Kluwer",
number = "1",

}

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TY - JOUR

T1 - Diagnostic reference levels, deterministic and stochastic risks in pediatric interventional cardiology procedures

AU - Rizk, Chadia

AU - Fares, Georges

AU - Vanhavere, Filip

AU - Saliba, Zakhia

AU - Farah, Jad

N1 - Score=10

PY - 2020/1/1

Y1 - 2020/1/1

N2 - To establish diagnostic reference levels (DRLs) and investigate deterministic and stochastic risks in pediatric interventional cardiology (IC) procedures. Exposure parameters were retrospectively reviewed for 373 patients treated between May 2016 and November 2018 at a single specialized hospital. Weight specific DRLs were derived for pediatric IC procedures. Additionally, peak skin dose (Dskin,max) was measured using thermoluminescent dosimeters for a sample of 7 diagnostic and 43 therapeutic procedures. Finally, using PCXMC software, organ doses were computed and the risk of exposure-induced cancer death (REID) was estimated using the risk models of the Biological Effects of Ionizing Radiation VII committee. DRLs for ventricular septal defect (VSD) occlusions, lacking in the literature, in terms of air kerma at patient entrance reference point (388 and 629 mGy) and total air kerma-area product (28 and 61 Gycm2) were proposed for patients weight-groups 5 − <15 kg and 15 − <30 kg, respectively. The mean (range) Dskin,max was 15 (1–30)mGy and 94 (1–491) mGy for diagnostic and therapeutic procedures, respectively. Meanwhile, VSDocclusion involved the highest organ doses where the lungs, liver, stomach, and breasts mean doses were 57, 37, 6, and 10 mGy, respectively, and the associated REID were 0.5% and 0.3% in female and male patients, respectively. DRLs were proposed for pediatric IC procedures; these will help optimize patient exposure. Dskin,max values were lower than the 2 Gy threshold for skin injuries. Pediatric organ doses and the REID were the highest during VSD occlusion and may be critical for repetitive procedures.

AB - To establish diagnostic reference levels (DRLs) and investigate deterministic and stochastic risks in pediatric interventional cardiology (IC) procedures. Exposure parameters were retrospectively reviewed for 373 patients treated between May 2016 and November 2018 at a single specialized hospital. Weight specific DRLs were derived for pediatric IC procedures. Additionally, peak skin dose (Dskin,max) was measured using thermoluminescent dosimeters for a sample of 7 diagnostic and 43 therapeutic procedures. Finally, using PCXMC software, organ doses were computed and the risk of exposure-induced cancer death (REID) was estimated using the risk models of the Biological Effects of Ionizing Radiation VII committee. DRLs for ventricular septal defect (VSD) occlusions, lacking in the literature, in terms of air kerma at patient entrance reference point (388 and 629 mGy) and total air kerma-area product (28 and 61 Gycm2) were proposed for patients weight-groups 5 − <15 kg and 15 − <30 kg, respectively. The mean (range) Dskin,max was 15 (1–30)mGy and 94 (1–491) mGy for diagnostic and therapeutic procedures, respectively. Meanwhile, VSDocclusion involved the highest organ doses where the lungs, liver, stomach, and breasts mean doses were 57, 37, 6, and 10 mGy, respectively, and the associated REID were 0.5% and 0.3% in female and male patients, respectively. DRLs were proposed for pediatric IC procedures; these will help optimize patient exposure. Dskin,max values were lower than the 2 Gy threshold for skin injuries. Pediatric organ doses and the REID were the highest during VSD occlusion and may be critical for repetitive procedures.

KW - operational topics

KW - children

KW - exposure

KW - radiation

KW - health effects

UR - http://ecm.sckcen.be/OTCS/llisapi.dll/open/36285529

U2 - 10.1097/HP.0000000000001114

DO - 10.1097/HP.0000000000001114

M3 - Article

VL - 118

SP - 85

EP - 95

JO - Health physics

JF - Health physics

SN - 0017-9078

IS - 1

ER -

ID: 5765942