Induction of neuronal apoptosis after prenatal irradiation in mice: an in vivo study

Research output: ThesisMaster's thesis

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Abstract

This study aimed to provide insight into early radiation-induced brain anomalies that might be related to previously observed cognitive and behavioural malfunctions in mice prenatally irradiated with moderate to high doses of X-radiation. More specifically, a disturbance of developental processes was investigated by means of immunohistochemical techniques in prenatally irradiated mouse embryos at the onset of neurogenesis (embryonic days 11 and 15).

Details

Original languageEnglish
Awarding Institution
  • KUL - Katholieke Universiteit Leuven
Supervisors/Advisors
  • Arckens, Lutgarde, Supervisor, External person
Place of PublicationMol, Belgium
Publisher
  • KUL - Katholieke Universiteit Leuven
Publication statusPublished - 30 Jan 2015

Keywords

  • neurogenesis, prenatal X-radiation, apoptosis, proliferation, mouse

ID: 337163