MADOR: a new tool to calculate decrease of effective doses in human after DTPA therapy

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Abstract

Abstract models have been developed to describe dissolution of Pu/Am/Cm after internal contamination by inhalation or wound, chelation of actinides by diethylene triamine penta acetic acid (DTPA) in different retention compartments and excretion of actinide–DTPA complexes. After coupling these models with those currently used for dose calculation, the modelling approach was assessed by fitting human data available in IDEAS database. Good fits were obtained for most studied cases, but further experimental studies are needed to validate some modelling hypotheses as well as the range of parameter values. From these first results, radioprotection tools are being developed: MAnagement of DOse Reduction after DTPA therapy.

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Original languageEnglish
Pages (from-to)371-375
JournalRadiation Protection Dosimetry
Volume144
Issue number1-4
DOIs
StatePublished - 1 Mar 2011

Keywords

  • MADOR: A NEW TOOLTO CALCULATE DECREASE OF EFFECTIVE DOSES IN HUMAN AFTER DTPA THERAPY

ID: 276454