Measuring genome conservation across taxa: divided strains and united kingdoms

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Measuring genome conservation across taxa: divided strains and united kingdoms. / Janssen, Paul; Kunin, Victor; Ahren, Dag; Goldovsky, Leonid; Ouzounis, Christos; Mergeay, Max (Peer reviewer); De Boever, Patrick (Peer reviewer).

In: Nucleic Acids Research, Vol. 33, No. 2, 28.01.2005, p. 616-621.

Research output: Contribution to journalArticle

Harvard

Janssen, P, Kunin, V, Ahren, D, Goldovsky, L, Ouzounis, C, Mergeay, M & De Boever, P 2005, 'Measuring genome conservation across taxa: divided strains and united kingdoms', Nucleic Acids Research, vol. 33, no. 2, pp. 616-621. https://doi.org/10.1093/nar/gki181

APA

Janssen, P., Kunin, V., Ahren, D., Goldovsky, L., Ouzounis, C., Mergeay, M., & De Boever, P. (2005). Measuring genome conservation across taxa: divided strains and united kingdoms. Nucleic Acids Research, 33(2), 616-621. https://doi.org/10.1093/nar/gki181

Vancouver

Janssen P, Kunin V, Ahren D, Goldovsky L, Ouzounis C, Mergeay M et al. Measuring genome conservation across taxa: divided strains and united kingdoms. Nucleic Acids Research. 2005 Jan 28;33(2):616-621. https://doi.org/10.1093/nar/gki181

Author

Janssen, Paul ; Kunin, Victor ; Ahren, Dag ; Goldovsky, Leonid ; Ouzounis, Christos ; Mergeay, Max ; De Boever, Patrick. / Measuring genome conservation across taxa: divided strains and united kingdoms. In: Nucleic Acids Research. 2005 ; Vol. 33, No. 2. pp. 616-621.

Bibtex - Download

@article{28962460aac04694ae89526af0c15304,
title = "Measuring genome conservation across taxa: divided strains and united kingdoms",
abstract = "Species evolutionary relationships have traditionally been defined bysequencesimilarities of phylogenetic marker molecules, recently followed by wholegenome phylogenies based on gene order, average ortholog similarity or gene content. Here, we introduce genome conservation—a novel metric of evolutionary distances between species that simultaneously takes into account, both gene content and sequence similarity at the whole-genome level. Genome conservation represents a robust distance measure, as demonstrated by accurate phylogenetic reconstructions. The genome conservation matrix for all presently sequenced organisms exhibits a remarkable ability to define evolutionary relationships across all taxonomic ranges. An assessment of taxonomic ranks with genome conservation shows that certain ranks are inadequately described and raises the possibility for a more precise and quantitative taxonomy in the future. All phylogenetic reconstructions are available at thegenomephylogenyserver:http://maine.ebi.ac.uk:8000/cgi-bin/gps/GPS.pl",
keywords = "molecular phylogeny, whole genome taxonomy, genome conservation, bioinformatics, evolution",
author = "Paul Janssen and Victor Kunin and Dag Ahren and Leonid Goldovsky and Christos Ouzounis and Max Mergeay and {De Boever}, Patrick",
note = "Score = 10",
year = "2005",
month = "1",
day = "28",
doi = "10.1093/nar/gki181",
language = "English",
volume = "33",
pages = "616--621",
journal = "Nucleic Acids Research",
issn = "0305-1048",
publisher = "Oxford University Press",
number = "2",

}

RIS - Download

TY - JOUR

T1 - Measuring genome conservation across taxa: divided strains and united kingdoms

AU - Janssen, Paul

AU - Kunin, Victor

AU - Ahren, Dag

AU - Goldovsky, Leonid

AU - Ouzounis, Christos

A2 - Mergeay, Max

A2 - De Boever, Patrick

N1 - Score = 10

PY - 2005/1/28

Y1 - 2005/1/28

N2 - Species evolutionary relationships have traditionally been defined bysequencesimilarities of phylogenetic marker molecules, recently followed by wholegenome phylogenies based on gene order, average ortholog similarity or gene content. Here, we introduce genome conservation—a novel metric of evolutionary distances between species that simultaneously takes into account, both gene content and sequence similarity at the whole-genome level. Genome conservation represents a robust distance measure, as demonstrated by accurate phylogenetic reconstructions. The genome conservation matrix for all presently sequenced organisms exhibits a remarkable ability to define evolutionary relationships across all taxonomic ranges. An assessment of taxonomic ranks with genome conservation shows that certain ranks are inadequately described and raises the possibility for a more precise and quantitative taxonomy in the future. All phylogenetic reconstructions are available at thegenomephylogenyserver:http://maine.ebi.ac.uk:8000/cgi-bin/gps/GPS.pl

AB - Species evolutionary relationships have traditionally been defined bysequencesimilarities of phylogenetic marker molecules, recently followed by wholegenome phylogenies based on gene order, average ortholog similarity or gene content. Here, we introduce genome conservation—a novel metric of evolutionary distances between species that simultaneously takes into account, both gene content and sequence similarity at the whole-genome level. Genome conservation represents a robust distance measure, as demonstrated by accurate phylogenetic reconstructions. The genome conservation matrix for all presently sequenced organisms exhibits a remarkable ability to define evolutionary relationships across all taxonomic ranges. An assessment of taxonomic ranks with genome conservation shows that certain ranks are inadequately described and raises the possibility for a more precise and quantitative taxonomy in the future. All phylogenetic reconstructions are available at thegenomephylogenyserver:http://maine.ebi.ac.uk:8000/cgi-bin/gps/GPS.pl

KW - molecular phylogeny

KW - whole genome taxonomy

KW - genome conservation

KW - bioinformatics

KW - evolution

UR - http://ecm.sckcen.be/OTCS/llisapi.dll/open/ezp_27235

UR - http://knowledgecentre.sckcen.be/so2/bibref/2862

U2 - 10.1093/nar/gki181

DO - 10.1093/nar/gki181

M3 - Article

VL - 33

SP - 616

EP - 621

JO - Nucleic Acids Research

JF - Nucleic Acids Research

SN - 0305-1048

IS - 2

ER -

ID: 157782