Abstract
Bacteria such as Cupriavidus metallidurans have developed different strategies for tolerating toxic levels of metal ions. Metal ion resistance requires the contribution of multiple layers of mechanisms, the most efficient being the efflux of the noxious cations out of the cell regulated by transport systems. Structural and functional data from bacterial primary and secondary transporters are outlined and detailed for the corresponding C. metallidurans proteins. Next, the available high-resolution threedimensional structures of C. metallidurans proteins involved in metal resistance mechanisms are reviewed and their structure-function relationship is discussed.
Details
| Original language | English |
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| Place of Publication | Switzerland |
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| Publisher | Springer |
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| Number of pages | 70 |
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| Edition | 1 |
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| ISBN (Print) | 978-3-319-20623-3 |
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| State | Published - Jul 2015 |
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| Name | SpringerBriefs in Biometals |
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