OpenDose: open access resources for nuclear medicine dosimetry

Research output: Contribution to journalArticle

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OpenDose: open access resources for nuclear medicine dosimetry. / Chauvin, Maxime; Borys, Damian; Botta, Francesca; Bzowski, Pawel; Dabin, Jérémie; Denis-Bacelar, Ana M.; Desbrée, Aurélie; Falzone, Nadia; Lee, Boon Quand; Mairani, Andrea ; Mathieu, Gilles; Malaroda, Alessandra; McKay, Erin; Mora-Ramirez, Erick ; Robinson, Andrew P.; Sarrut, David; Struelens, Lara; Vergara Gil, A.; Bardiès, Manuel.

In: Journal of Nuclear Medicine, Vol. 61, No. 10, 240366, 10.2020, p. 1514-1519.

Research output: Contribution to journalArticle

Harvard

Chauvin, M, Borys, D, Botta, F, Bzowski, P, Dabin, J, Denis-Bacelar, AM, Desbrée, A, Falzone, N, Lee, BQ, Mairani, A, Mathieu, G, Malaroda, A, McKay, E, Mora-Ramirez, E, Robinson, AP, Sarrut, D, Struelens, L, Vergara Gil, A & Bardiès, M 2020, 'OpenDose: open access resources for nuclear medicine dosimetry', Journal of Nuclear Medicine, vol. 61, no. 10, 240366, pp. 1514-1519. https://doi.org/10.2967/jnumed.119.240366

APA

Chauvin, M., Borys, D., Botta, F., Bzowski, P., Dabin, J., Denis-Bacelar, A. M., ... Bardiès, M. (2020). OpenDose: open access resources for nuclear medicine dosimetry. Journal of Nuclear Medicine, 61(10), 1514-1519. [240366]. https://doi.org/10.2967/jnumed.119.240366

Vancouver

Chauvin M, Borys D, Botta F, Bzowski P, Dabin J, Denis-Bacelar AM et al. OpenDose: open access resources for nuclear medicine dosimetry. Journal of Nuclear Medicine. 2020 Oct;61(10):1514-1519. 240366. https://doi.org/10.2967/jnumed.119.240366

Author

Chauvin, Maxime ; Borys, Damian ; Botta, Francesca ; Bzowski, Pawel ; Dabin, Jérémie ; Denis-Bacelar, Ana M. ; Desbrée, Aurélie ; Falzone, Nadia ; Lee, Boon Quand ; Mairani, Andrea ; Mathieu, Gilles ; Malaroda, Alessandra ; McKay, Erin ; Mora-Ramirez, Erick ; Robinson, Andrew P. ; Sarrut, David ; Struelens, Lara ; Vergara Gil, A. ; Bardiès, Manuel. / OpenDose: open access resources for nuclear medicine dosimetry. In: Journal of Nuclear Medicine. 2020 ; Vol. 61, No. 10. pp. 1514-1519.

Bibtex - Download

@article{5684729ef5b943ef8036d772e9ea53a7,
title = "OpenDose: open access resources for nuclear medicine dosimetry",
abstract = "Background: Radiopharmaceutical dosimetry depends on the localization in space and time of radioactive sources and requires the estimation of the amount of energy emitted by the sources deposited within targets. In particular, when computing resources are not accessible, this task can be carried out using precomputed tables of Specific Absorbed Fractions (SAFs) or S values based on dosimetric models. The OpenDose collaboration aims to generate and make freely available a range of dosimetric data and tools. Methods: OpenDose brings together resources and expertise from 18 international teams to produce and compare traceable dosimetric data using 6 of the most popular Monte Carlo codes in radiation transport (EGSnrc/EGS++, FLUKA, GATE, Geant4, MCNP/MCNPX and PENELOPE). SAFs are uploaded, together with their associated statistical uncertainties, in a relational database. S values are then calculated from mono-energetic SAFs, based on the radioisotope decay data presented in the International Commission on Radiological Protection(ICRP) publication 107.Results: The OpenDose collaboration produced SAFs for all source regions and targets combinations of the two ICRP 110 adult reference models. SAFs computed from the different Monte Carlo codes were in good agreement at all energies, with standard deviations below individual statistical uncertainties. Calculated S values were in good agreement with OLINDA 2 (commercial) and IDAC 2.1 (free) software. A dedicated website (www.opendose.org) has beendeveloped to provide easy and open access to all data. Conclusion: The OpenDose website allows the display and download of SAFs and the corresponding S values for 1252 radionuclides. The OpenDose collaboration, open to new research teams, will extend data production to other dosimetric models and implement new free features, such as online dosimetric tools and patient-specific absorbed dose calculation software, together with educational resources.",
keywords = "Radiation Physics, Radiobiology, Dosimetry, Radionuclide therapy, Monte Carlo methods, Open-access database",
author = "Maxime Chauvin and Damian Borys and Francesca Botta and Pawel Bzowski and J{\'e}r{\'e}mie Dabin and Denis-Bacelar, {Ana M.} and Aur{\'e}lie Desbr{\'e}e and Nadia Falzone and Lee, {Boon Quand} and Andrea Mairani and Gilles Mathieu and Alessandra Malaroda and Erin McKay and Erick Mora-Ramirez and Robinson, {Andrew P.} and David Sarrut and Lara Struelens and {Vergara Gil}, A. and Manuel Bardi{\`e}s",
note = "Score=10",
year = "2020",
month = "10",
doi = "10.2967/jnumed.119.240366",
language = "English",
volume = "61",
pages = "1514--1519",
journal = "Journal of Nuclear Medicine",
issn = "0161-5505",
publisher = "SNMMI - Society of Nuclear Medicine and Molecular Imaging",
number = "10",

}

RIS - Download

TY - JOUR

T1 - OpenDose: open access resources for nuclear medicine dosimetry

AU - Chauvin, Maxime

AU - Borys, Damian

AU - Botta, Francesca

AU - Bzowski, Pawel

AU - Dabin, Jérémie

AU - Denis-Bacelar, Ana M.

AU - Desbrée, Aurélie

AU - Falzone, Nadia

AU - Lee, Boon Quand

AU - Mairani, Andrea

AU - Mathieu, Gilles

AU - Malaroda, Alessandra

AU - McKay, Erin

AU - Mora-Ramirez, Erick

AU - Robinson, Andrew P.

AU - Sarrut, David

AU - Struelens, Lara

AU - Vergara Gil, A.

AU - Bardiès, Manuel

N1 - Score=10

PY - 2020/10

Y1 - 2020/10

N2 - Background: Radiopharmaceutical dosimetry depends on the localization in space and time of radioactive sources and requires the estimation of the amount of energy emitted by the sources deposited within targets. In particular, when computing resources are not accessible, this task can be carried out using precomputed tables of Specific Absorbed Fractions (SAFs) or S values based on dosimetric models. The OpenDose collaboration aims to generate and make freely available a range of dosimetric data and tools. Methods: OpenDose brings together resources and expertise from 18 international teams to produce and compare traceable dosimetric data using 6 of the most popular Monte Carlo codes in radiation transport (EGSnrc/EGS++, FLUKA, GATE, Geant4, MCNP/MCNPX and PENELOPE). SAFs are uploaded, together with their associated statistical uncertainties, in a relational database. S values are then calculated from mono-energetic SAFs, based on the radioisotope decay data presented in the International Commission on Radiological Protection(ICRP) publication 107.Results: The OpenDose collaboration produced SAFs for all source regions and targets combinations of the two ICRP 110 adult reference models. SAFs computed from the different Monte Carlo codes were in good agreement at all energies, with standard deviations below individual statistical uncertainties. Calculated S values were in good agreement with OLINDA 2 (commercial) and IDAC 2.1 (free) software. A dedicated website (www.opendose.org) has beendeveloped to provide easy and open access to all data. Conclusion: The OpenDose website allows the display and download of SAFs and the corresponding S values for 1252 radionuclides. The OpenDose collaboration, open to new research teams, will extend data production to other dosimetric models and implement new free features, such as online dosimetric tools and patient-specific absorbed dose calculation software, together with educational resources.

AB - Background: Radiopharmaceutical dosimetry depends on the localization in space and time of radioactive sources and requires the estimation of the amount of energy emitted by the sources deposited within targets. In particular, when computing resources are not accessible, this task can be carried out using precomputed tables of Specific Absorbed Fractions (SAFs) or S values based on dosimetric models. The OpenDose collaboration aims to generate and make freely available a range of dosimetric data and tools. Methods: OpenDose brings together resources and expertise from 18 international teams to produce and compare traceable dosimetric data using 6 of the most popular Monte Carlo codes in radiation transport (EGSnrc/EGS++, FLUKA, GATE, Geant4, MCNP/MCNPX and PENELOPE). SAFs are uploaded, together with their associated statistical uncertainties, in a relational database. S values are then calculated from mono-energetic SAFs, based on the radioisotope decay data presented in the International Commission on Radiological Protection(ICRP) publication 107.Results: The OpenDose collaboration produced SAFs for all source regions and targets combinations of the two ICRP 110 adult reference models. SAFs computed from the different Monte Carlo codes were in good agreement at all energies, with standard deviations below individual statistical uncertainties. Calculated S values were in good agreement with OLINDA 2 (commercial) and IDAC 2.1 (free) software. A dedicated website (www.opendose.org) has beendeveloped to provide easy and open access to all data. Conclusion: The OpenDose website allows the display and download of SAFs and the corresponding S values for 1252 radionuclides. The OpenDose collaboration, open to new research teams, will extend data production to other dosimetric models and implement new free features, such as online dosimetric tools and patient-specific absorbed dose calculation software, together with educational resources.

KW - Radiation Physics

KW - Radiobiology

KW - Dosimetry

KW - Radionuclide therapy

KW - Monte Carlo methods

KW - Open-access database

UR - https://ecm.sckcen.be/OTCS/llisapi.dll?func=ll&objId=43084514&objAction=download

U2 - 10.2967/jnumed.119.240366

DO - 10.2967/jnumed.119.240366

M3 - Article

VL - 61

SP - 1514

EP - 1519

JO - Journal of Nuclear Medicine

JF - Journal of Nuclear Medicine

SN - 0161-5505

IS - 10

M1 - 240366

ER -

ID: 7089585