Out of Field dose measurements for 3D confromal and intensity modulated radiotherapy of paediatric brain tumour

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Out of Field dose measurements for 3D confromal and intensity modulated radiotherapy of paediatric brain tumour. / Majer, Marija; Stolarczyk, Liliana; De Saint-Hubert, Marijke; Kabat, Damian; Knezevic, Zeljka; Miljanic, Saveta; Mojz˙eszek, Natalia; Harrison, Roger.

In: Radiation protection dosimetry, Vol. 176, No. 3, 01.11.2017, p. 331-340.

Research output: Contribution to journalArticle

Harvard

Majer, M, Stolarczyk, L, De Saint-Hubert, M, Kabat, D, Knezevic, Z, Miljanic, S, Mojz˙eszek, N & Harrison, R 2017, 'Out of Field dose measurements for 3D confromal and intensity modulated radiotherapy of paediatric brain tumour', Radiation protection dosimetry, vol. 176, no. 3, pp. 331-340. https://doi.org/10.1093/rpd/ncx015

APA

Majer, M., Stolarczyk, L., De Saint-Hubert, M., Kabat, D., Knezevic, Z., Miljanic, S., ... Harrison, R. (2017). Out of Field dose measurements for 3D confromal and intensity modulated radiotherapy of paediatric brain tumour. Radiation protection dosimetry, 176(3), 331-340. https://doi.org/10.1093/rpd/ncx015

Vancouver

Majer M, Stolarczyk L, De Saint-Hubert M, Kabat D, Knezevic Z, Miljanic S et al. Out of Field dose measurements for 3D confromal and intensity modulated radiotherapy of paediatric brain tumour. Radiation protection dosimetry. 2017 Nov 1;176(3):331-340. https://doi.org/10.1093/rpd/ncx015

Author

Majer, Marija ; Stolarczyk, Liliana ; De Saint-Hubert, Marijke ; Kabat, Damian ; Knezevic, Zeljka ; Miljanic, Saveta ; Mojz˙eszek, Natalia ; Harrison, Roger. / Out of Field dose measurements for 3D confromal and intensity modulated radiotherapy of paediatric brain tumour. In: Radiation protection dosimetry. 2017 ; Vol. 176, No. 3. pp. 331-340.

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@article{42c50b9866554b079007c12fb7d6a97b,
title = "Out of Field dose measurements for 3D confromal and intensity modulated radiotherapy of paediatric brain tumour",
abstract = "The purpose of this study was to measure out-of-field organ doses in clinical conditions in anthropomorphic paediatric phantoms which received a simulated treatment of a brain tumour with intensity modulated radiotherapy (IMRT) and 3D conformal radiotherapy (3D CRT). Organ doses measured with radiophotoluminescent and thermoluminescent dosemeters were on average 1.6 and 3.0 times higher for the 5 y-old than for the 10 y-old phantom for IMRT and 3D CRT, respectively. A larger 5-y to 10-y organ dose ratio for 3D CRT can be explained because the use of a mechanical wedge for the 5-y-old 3D CRT phantom treatment increased out-of-field doses. Due to different configurations of the radiation fields, for both phantoms, the IMRT technique resulted in a higher non-target brain dose and higher eye doses but lower thyroid doses compared to 3D CRT. For 3D CRT (which used a non-coplanar field configuration), eye doses were 3-6{\%} and for IMRT (which used a coplanar field configuration) 27-30{\%} of the treatment dose, respectively. For thyroid and more distant organs, doses were less than 1{\%} of the treatment dose. Comparison of measured doses and doses calculated by the treatment planning system (TPS) showed that the TPS underestimated out-of-field doses both for IMRT and 3D CRT.",
keywords = "Radiotherapy, out-of-field dose, children, Brain tumor",
author = "Marija Majer and Liliana Stolarczyk and {De Saint-Hubert}, Marijke and Damian Kabat and Zeljka Knezevic and Saveta Miljanic and Natalia Mojz˙eszek and Roger Harrison",
note = "score=10",
year = "2017",
month = "11",
day = "1",
doi = "10.1093/rpd/ncx015",
language = "English",
volume = "176",
pages = "331--340",
journal = "Radioation Protection Dosimitry",
issn = "0144-8420",
publisher = "Oxford University Press",
number = "3",

}

RIS - Download

TY - JOUR

T1 - Out of Field dose measurements for 3D confromal and intensity modulated radiotherapy of paediatric brain tumour

AU - Majer, Marija

AU - Stolarczyk, Liliana

AU - De Saint-Hubert, Marijke

AU - Kabat, Damian

AU - Knezevic, Zeljka

AU - Miljanic, Saveta

AU - Mojz˙eszek, Natalia

AU - Harrison, Roger

N1 - score=10

PY - 2017/11/1

Y1 - 2017/11/1

N2 - The purpose of this study was to measure out-of-field organ doses in clinical conditions in anthropomorphic paediatric phantoms which received a simulated treatment of a brain tumour with intensity modulated radiotherapy (IMRT) and 3D conformal radiotherapy (3D CRT). Organ doses measured with radiophotoluminescent and thermoluminescent dosemeters were on average 1.6 and 3.0 times higher for the 5 y-old than for the 10 y-old phantom for IMRT and 3D CRT, respectively. A larger 5-y to 10-y organ dose ratio for 3D CRT can be explained because the use of a mechanical wedge for the 5-y-old 3D CRT phantom treatment increased out-of-field doses. Due to different configurations of the radiation fields, for both phantoms, the IMRT technique resulted in a higher non-target brain dose and higher eye doses but lower thyroid doses compared to 3D CRT. For 3D CRT (which used a non-coplanar field configuration), eye doses were 3-6% and for IMRT (which used a coplanar field configuration) 27-30% of the treatment dose, respectively. For thyroid and more distant organs, doses were less than 1% of the treatment dose. Comparison of measured doses and doses calculated by the treatment planning system (TPS) showed that the TPS underestimated out-of-field doses both for IMRT and 3D CRT.

AB - The purpose of this study was to measure out-of-field organ doses in clinical conditions in anthropomorphic paediatric phantoms which received a simulated treatment of a brain tumour with intensity modulated radiotherapy (IMRT) and 3D conformal radiotherapy (3D CRT). Organ doses measured with radiophotoluminescent and thermoluminescent dosemeters were on average 1.6 and 3.0 times higher for the 5 y-old than for the 10 y-old phantom for IMRT and 3D CRT, respectively. A larger 5-y to 10-y organ dose ratio for 3D CRT can be explained because the use of a mechanical wedge for the 5-y-old 3D CRT phantom treatment increased out-of-field doses. Due to different configurations of the radiation fields, for both phantoms, the IMRT technique resulted in a higher non-target brain dose and higher eye doses but lower thyroid doses compared to 3D CRT. For 3D CRT (which used a non-coplanar field configuration), eye doses were 3-6% and for IMRT (which used a coplanar field configuration) 27-30% of the treatment dose, respectively. For thyroid and more distant organs, doses were less than 1% of the treatment dose. Comparison of measured doses and doses calculated by the treatment planning system (TPS) showed that the TPS underestimated out-of-field doses both for IMRT and 3D CRT.

KW - Radiotherapy

KW - out-of-field dose

KW - children

KW - Brain tumor

UR - http://ecm.sckcen.be/OTCS/llisapi.dll/open/23107341

U2 - 10.1093/rpd/ncx015

DO - 10.1093/rpd/ncx015

M3 - Article

VL - 176

SP - 331

EP - 340

JO - Radioation Protection Dosimitry

JF - Radioation Protection Dosimitry

SN - 0144-8420

IS - 3

ER -

ID: 2368080