Research output: Contribution to report/book/conference proceedings › Chapter › peer-review
Plasmids as secondary chromosomes. / Van Houdt, Rob; Mergeay, Max.
Molecular Life Sciences: An Encyclopedic Reference. Vol. 12 1. ed. Germany : Springer, 2012. p. 1-4.Research output: Contribution to report/book/conference proceedings › Chapter › peer-review
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TY - CHAP
T1 - Plasmids as secondary chromosomes
AU - Van Houdt, Rob
AU - Mergeay, Max
N1 - Score = 3
PY - 2012/10
Y1 - 2012/10
N2 - Large replicons secondary to the main chromosome have been termed both 'second chromosomes' if they carry essential genes and are indispensable for cell viability, as well as 'megaplasmids' if they do not use chromosome-type but plasmid-type replication systems. Recently, the term "chromid" was introduced to distinguish this replicon as it is neither a chromosome nor a plasmid. Three criteria were defined: (i) chromids have plasmid-type maintenance and replication systems, (ii) chromids have a nucleotide composition close to that of the chromosome and (iii) chromids carry core genes that are found on the chromosome in other species (Harrison et al., 2010). Although this adds to the complexity of the nomenclature found in the literature, it reflects the necessity to clearly differentiate these types of replicons.
AB - Large replicons secondary to the main chromosome have been termed both 'second chromosomes' if they carry essential genes and are indispensable for cell viability, as well as 'megaplasmids' if they do not use chromosome-type but plasmid-type replication systems. Recently, the term "chromid" was introduced to distinguish this replicon as it is neither a chromosome nor a plasmid. Three criteria were defined: (i) chromids have plasmid-type maintenance and replication systems, (ii) chromids have a nucleotide composition close to that of the chromosome and (iii) chromids carry core genes that are found on the chromosome in other species (Harrison et al., 2010). Although this adds to the complexity of the nomenclature found in the literature, it reflects the necessity to clearly differentiate these types of replicons.
KW - chromid
KW - secondary chromosome
KW - megaplasmid
UR - http://ecm.sckcen.be/OTCS/llisapi.dll/open/ezp_121811
UR - http://knowledgecentre.sckcen.be/so2/bibref/9700
M3 - Chapter
VL - 12
SP - 1
EP - 4
BT - Molecular Life Sciences: An Encyclopedic Reference
PB - Springer
CY - Germany
ER -
ID: 278414