Production of intense mass separated $^{11}$C beams for PET-aided hadron therapy

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  • KUL - Katholieke Universiteit Leuven
  • CERN - Conseil Européen pour la Recherche Nucléaire

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A novel production system based on the ISOL method is being
developed to produce intense mass separated $^{11}$C beams for PET-aided
hadron therapy. This work presents a systematic study on the target-ion
source developments optimized for $^{11}$C beam production. A solid
boron nitride target (BN) with approximately 21$\%$ open porosity was
manufactured by spark plasma sintering to provide maximized in-target
production yield with enhanced isotope release properties. Operational
limitations with respect to high temperatures and oxidizing atmospheres
were studied, revealing that the BN target can withstand temperatures up
to 1500 $\degree$C and can be operated with a controlled O$_2$ leak,
providing O$_2$ potentials up to $-$300 kJ/mol, measured at 1000


Original languageEnglish
Pages (from-to)403-407
Number of pages5
JournalNuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms
Early online date30 May 2019
Publication statusPublished - 15 Jan 2020


  • radioactive ion beam production, Radioactive Ion Beams, C-11 production, target material, ISOL, medical isotopes production

ID: 5380910