Production of intense mass separated $^{11}$C beams for PET-aided hadron therapy

Research output: Contribution to journalArticle

Standard

Production of intense mass separated $^{11}$C beams for PET-aided hadron therapy. / Stegemann, Simon; Cocolios, Thomas Elias; Dockx, Kristof; Leinders, Gregory; Popescu, Lucia; Fernandes Pinto Ramos, João Pedro; Verwerft, Marc; Rijpstra, Kim; Stora, Thierry; Vleugels, Jef.

In: Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, Vol. 463, 15.01.2020, p. 403-407.

Research output: Contribution to journalArticle

Harvard

Stegemann, S, Cocolios, TE, Dockx, K, Leinders, G, Popescu, L, Fernandes Pinto Ramos, JP, Verwerft, M, Rijpstra, K, Stora, T & Vleugels, J 2020, 'Production of intense mass separated $^{11}$C beams for PET-aided hadron therapy', Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, vol. 463, pp. 403-407. https://doi.org/10.1016/j.nimb.2019.04.042

APA

Stegemann, S., Cocolios, T. E., Dockx, K., Leinders, G., Popescu, L., Fernandes Pinto Ramos, J. P., ... Vleugels, J. (2020). Production of intense mass separated $^{11}$C beams for PET-aided hadron therapy. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms, 463, 403-407. https://doi.org/10.1016/j.nimb.2019.04.042

Vancouver

Stegemann S, Cocolios TE, Dockx K, Leinders G, Popescu L, Fernandes Pinto Ramos JP et al. Production of intense mass separated $^{11}$C beams for PET-aided hadron therapy. Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. 2020 Jan 15;463:403-407. https://doi.org/10.1016/j.nimb.2019.04.042

Author

Stegemann, Simon ; Cocolios, Thomas Elias ; Dockx, Kristof ; Leinders, Gregory ; Popescu, Lucia ; Fernandes Pinto Ramos, João Pedro ; Verwerft, Marc ; Rijpstra, Kim ; Stora, Thierry ; Vleugels, Jef. / Production of intense mass separated $^{11}$C beams for PET-aided hadron therapy. In: Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. 2020 ; Vol. 463. pp. 403-407.

Bibtex - Download

@article{80433c7a3e91457988ff5a11913706fe,
title = "Production of intense mass separated $^{11}$C beams for PET-aided hadron therapy",
abstract = "A novel production system based on the ISOL method is beingdeveloped to produce intense mass separated $^{11}$C beams for PET-aidedhadron therapy. This work presents a systematic study on the target-ionsource developments optimized for $^{11}$C beam production. A solidboron nitride target (BN) with approximately 21$\{\%}$ open porosity wasmanufactured by spark plasma sintering to provide maximized in-targetproduction yield with enhanced isotope release properties. Operationallimitations with respect to high temperatures and oxidizing atmosphereswere studied, revealing that the BN target can withstand temperatures upto 1500 $\degree$C and can be operated with a controlled O$_2$ leak,providing O$_2$ potentials up to $-$300 kJ/mol, measured at 1000$\degree$C.",
keywords = "radioactive ion beam production, Radioactive Ion Beams, C-11 production, target material, ISOL, medical isotopes production",
author = "Simon Stegemann and Cocolios, {Thomas Elias} and Kristof Dockx and Gregory Leinders and Lucia Popescu and {Fernandes Pinto Ramos}, {Jo{\~a}o Pedro} and Marc Verwerft and Kim Rijpstra and Thierry Stora and Jef Vleugels",
note = "Score=10",
year = "2020",
month = "1",
day = "15",
doi = "10.1016/j.nimb.2019.04.042",
language = "English",
volume = "463",
pages = "403--407",
journal = "Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms",
issn = "0168-583X",
publisher = "Elsevier",

}

RIS - Download

TY - JOUR

T1 - Production of intense mass separated $^{11}$C beams for PET-aided hadron therapy

AU - Stegemann, Simon

AU - Cocolios, Thomas Elias

AU - Dockx, Kristof

AU - Leinders, Gregory

AU - Popescu, Lucia

AU - Fernandes Pinto Ramos, João Pedro

AU - Verwerft, Marc

AU - Rijpstra, Kim

AU - Stora, Thierry

AU - Vleugels, Jef

N1 - Score=10

PY - 2020/1/15

Y1 - 2020/1/15

N2 - A novel production system based on the ISOL method is beingdeveloped to produce intense mass separated $^{11}$C beams for PET-aidedhadron therapy. This work presents a systematic study on the target-ionsource developments optimized for $^{11}$C beam production. A solidboron nitride target (BN) with approximately 21$\%$ open porosity wasmanufactured by spark plasma sintering to provide maximized in-targetproduction yield with enhanced isotope release properties. Operationallimitations with respect to high temperatures and oxidizing atmosphereswere studied, revealing that the BN target can withstand temperatures upto 1500 $\degree$C and can be operated with a controlled O$_2$ leak,providing O$_2$ potentials up to $-$300 kJ/mol, measured at 1000$\degree$C.

AB - A novel production system based on the ISOL method is beingdeveloped to produce intense mass separated $^{11}$C beams for PET-aidedhadron therapy. This work presents a systematic study on the target-ionsource developments optimized for $^{11}$C beam production. A solidboron nitride target (BN) with approximately 21$\%$ open porosity wasmanufactured by spark plasma sintering to provide maximized in-targetproduction yield with enhanced isotope release properties. Operationallimitations with respect to high temperatures and oxidizing atmosphereswere studied, revealing that the BN target can withstand temperatures upto 1500 $\degree$C and can be operated with a controlled O$_2$ leak,providing O$_2$ potentials up to $-$300 kJ/mol, measured at 1000$\degree$C.

KW - radioactive ion beam production

KW - Radioactive Ion Beams

KW - C-11 production

KW - target material

KW - ISOL

KW - medical isotopes production

UR - http://ecm.sckcen.be/OTCS/llisapi.dll/open/34793064

U2 - 10.1016/j.nimb.2019.04.042

DO - 10.1016/j.nimb.2019.04.042

M3 - Article

VL - 463

SP - 403

EP - 407

JO - Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms

JF - Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms

SN - 0168-583X

ER -

ID: 5380910