Research Report : Study of the solubility of Duolife® and preliminary tests on its effect on human cancer cells.

Research output: Report/bookER - External report

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Abstract

Over the past 15 years, some potential anticarcinogenic and anti-inflammatory effects of antioxidants have been defined. Antioxidants are known to act as powerful free-radical scavengers. Free radicals are able to induce DNA strand breaks and oxidative modifications of DNA bases and are produced naturally in the cell following a stress or respiration. The present preliminary study was undertaken in order to explore whether the product Duolife containing antioxidants could enhance apoptosis (or programmed cell death) in cancerous cells. Duolife was tested on two human cancerous cell lines: HELA (derived from cervix carcinoma) and IM-9 (derived from multiple myeloma) at various concentrations ranging from 0 to 500 µg/mL. The parameters investigated were cell proliferation, morphological changes and apoptosis.

Details

Original languageEnglish
PublisherSCK•CEN - Studiecentrum voor Kernenergie/Centre d’Etude de l’Energie Nucléaire
Number of pages34
Volume1
Edition0
StatePublished - 15 May 2006

Publication series

NameSCK•CEN Reports
PublisherStudiecentrum voor Kernenergie
No.ER-100

Keywords

  • antioxidant, duolife

ID: 273211